Nineteen of 30 Dow members finished in negative territory.
The Dow Jones Industrial Average was down 25 points, or 0.12%, to 20,812, the S&P 500 had lost six points, or 0.26%, to 2,364 and the Nasdaq Composite had dropped 36 points, or 0.62%, to 5,825.
The Dow's record-setting run finally came to an end Tuesday, as stocks ran into stiff resistance ahead of planned remarks from President Trump.
Also weighing on sentiment was data that showed U.S. economic growth slowed in the fourth quarter.
However, clouding the issue, the U.S. fourth-quarter gross domestic product reading remained unchanged at 1.9% to miss expectations of a 2.1% upward revision.
Philadelphia Fed President Patrick Harker is due to address the economic outlook at Temple University at 3 p.m.
"Sentiment keeps improving", McMillan said.
The ISM said its purchasing managers index climbed to 57.7 in February from 56.0 in January, with a reading above 50 indicating growth in the manufacturing sector. Economists had expected the index to edge down to 110.9.
Reliance Jio Unveils Prime Membership Plans and Tariff
If you're on any other screen, just tap on the three-horizontal lines menu button on the top left, and tap on Jio Prime . Apart from Samsung, Jio recently joined hands with US-based Cisco for sourcing networking solutions.
Should India Make Changes for the Second Test vs Australia?
The Test match finished inside three days with the pitch showing signs of deterioration and crumbling right from the outset. Local reports in India claim the BCCI's chief curator Daljit Singh could be sacked for the role he played in the saga.
On the currency markets, the dollar rose 0.2 percent against the yen, while the British pound hit a six-week low of $1.2261 following renewed Brexit fears and disappointing data out of the United Kingdom on Wednesday. The index fell to its lowest closing level in nearly a month.
Utilities posted some of the biggest losses in early trading.
Target tumbled after the retailer fell short on revenue and earnings forecast.
Overseas markets also reacted positively.
In Hong Kong, the Hang Seng index was up 0.19%.
Elsewhere, benchmark indexes in Indonesia and Malaysia were up more than 1 percent. A key dollar index dipped 0.1% on the day.
In the bond market, treasuries moved back to the upside following the pullback seen in the previous session. The S&P is up about 10.5 percent since the November 8 election. He noted Trump floated the idea of as much as $1 trillion in infrastructure investment, though that will be hard to get approved by Congress. Personal income rose 0.4% in January, which was above expectations; while consumer spending slowed down.
Chinese shares bucked the regional trend to end lower after a string of hawkish remarks from Federal Reserve officials stirred concerns that an interest rate hike in the USA could trigger fresh capital outflows and hurt domestic liquidity.
Saudi Arabia is the Arab world's largest economy and exports more oil than any other country in the world. Indonesia is the second leg of his month-long, six-nation tour in Asia that started last week.
Earlier Wednesday, a USA commander accused Russian and Syrian jets of bombing US-backed fighters in Syria. The United States now has about 500 troops in Syria, nearly all of them special operations commandos.
As per the Wall Street Journal , Snap has made up its mind as to its final IPO valuation and per share price. The company is also reportedly focused on boosting revenue per user, not on becoming globally ubiquitous.
Western Mosul has almost 750,000 civilians who remain inside the city, and ISIS is deeply embedded within their neighborhoods. Those still in Mosul have to face Daesh's strict rule along with a lack of basic goods and the danger from the fighting.
Asked how much he had to drink, Parry told the officers "a lot" and "more than I should have been", according to the report. Parry was a fifth-round pick out of Stanford in 2015, and has started every game the past two years for the Colts.
They plan on doing a not-so-sequel follow-up to the 2011 game they released based on James Cameron's 3D movie of the same name. Ubisoft did say that this untitled Avatar game will be available on consoles and Windows 10 PCs.
" Dancing with the Stars " announced the cast for their new season and it includes not one, but two former Olympians. However, we can't help but point out that Heather has quite a dancing background - enough to be a pro on the show!
Land Rover unveils the new Range Rover Velar
The Velar hits 60 miles per hour from a stop in a sports car-like 5.3 seconds in its fastest configuration. In 1969, development engineers began testing preproduction prototypes of the original Range Rover.
Southland Christians To Observe Ash Wednesday
The group's message ignited the enthusiasm of staff at the First Congregational United Church of Christ, 20 Oak Street. Catholics traditionally attend a Mass at which their foreheads are marked with ash in the shape of a cross.
Billion Year Old Fossil Means Life On Mars Is Likely
The iron-eating fossil bacteria were extracted from rocks recovered from the Nuvvuagittuq Supracrustal Belt in Quebec. Stronger evidence for ancient fossils comes from several findings in rocks at around 3.5 billion years old, she said.
In France Election turns ugly as political attacks mount
Penelope was also employed at an art magazine from May 2012 to December 2013, where she was paid roughly 5,000 euros a month. An Opinionway poll on Wednesday showed Fillon in third place at 21%, Macron at 24% and Le Pen at 25% in the first round.
Xbox Game Pass Announced, $9.99 Offers Over 100 Titles
With EA Access and Origin Access you get a huge assortment of incredible EA games on your PC or Xbox One for a low, flat rate. To be clear, this isn't a streaming service - you download the games on your Xbox hard drive and launch them locally.
Al Qaeda deputy leader reportedly killed in Syria
Al-Qaeda deputy leader Abu al-Khayr al-Masri has been killed in a U.S drone strike near Al-Mastoumeh in #Idlib . The importance of Masri's death is being hyped by some as the biggest death in al-Qaeda since Osama bin Laden.
Trump executive order targets clean water rule
Critics contend the rule crafted by the Obama administration could apply to ditches and small isolated bodies of water. The rule gives protection to 60 percent of the US's bodies of water, including wetlands.
USB-eh? iPhone 8 to 'ditch Lightning connector for USB-C'
We are not sure about how accurate this report is that Apple may replace their Lightning port on the iPhone with USB Type C. According to a report by the WSJ , Apple might do away with the Lightning connector for the universal Type-C USB.